The 49ers have revealed their latest injury report before their Sunday Night Football tilt against the Buffalo Bills.

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there ...

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Despite ...

The banged-up San Francisco 49ers received some positive news on Wednesday. Per ESPN's Nick Wagoner, 49ers head coach Kyle ...

Kyle Shanahan gave an answer at his press conference on Wednesday that indicates why the 49ers are utilizing Christian ...

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...

Head coach Kyle Shanahan explains why the 49ers don't rotate their running backs to give Christian McCaffrey a breather.

San Francisco 49ers star Fred Warner told reporters Wednesday that he fractured an ankle on Oct. 29 and has been receiving ...

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

Limited, but barely throws Wednesday ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...