While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...

Sunday could be the day Douglas has been waiting for -- because Milano is closing in on his return. The 30-year-old was a ...

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

The 49ers have revealed their latest injury report before their Sunday Night Football tilt against the Buffalo Bills.

Traffic and road closure information for Sunday’s Buffalo Bills game against the San Francisco 49ers has been announced by ...

San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

Following their bye week, the Bills (9-2) will take on the San Francisco 49ers (5-6) at Highmark Stadium in Week 13. But ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

There is a High Risk of Weather Impact (ROWI) for the NFL's Sunday Night Football matchup between the San Francisco 49ers ...